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{
    "id": 907180,
    "url": "https://info.mzalendo.com/api/v0.1/hansard/entries/907180/?format=api",
    "text_counter": 718,
    "type": "speech",
    "speaker_name": "Sen. (Prof.) Ongeri",
    "speaker_title": "",
    "speaker": {
        "id": 124,
        "legal_name": "Samson Kegeo Ongeri",
        "slug": "samson-ongeri"
    },
    "content": "When I was a doctor, I used to see most of them. The ones who had the recessive type of the disease particularly would have one crisis after the other. What are the crises? It is the ability for these cells to clot in the narrowest level of the blood vessels. Therefore, they may be deposited in the brain or lungs causing a brain cardiovascular accident. They may be deposited in the lungs causing accidents such as difficulties in breathing. They may be deposited in the heart itself causing hear failure or heart attack. They may be deposited in the spleen because it is the one that collects all the garbage in the process of moping it up. So, one of the symptoms that is shown is that it gets enlarged which is called splenomegaly. With time, it enlarges. You can do a splenectomy or remove the spleen, but it does not cure the problem. This means that unless we put in place elements that will make these children survive, they will succumb to death at a very early age. One of the things that is done even at that early age when they have this abnormal haemoglobin – the Sickle Cell Disease – the ability to carry oxygen is heavily impaired and compromised. In various clinics, doctors know that there is simple basic medication. One of the simplest drugs that will be used to ensure they live as near normal life as possible is hydroxyurea. In other words, it is urea, but the hydroxyl has extra hydroxyl carbons. This drug is capable of creating foetal haemoglobin. In other words, when a child is born, the type of haemoglobin before it changes to adult haemoglobin is the one of a young child. The foetal haemoglobin has the capacity to carry oxygen to all parts of the body. This drug is able to create new foetal haemoglobin that helps particularly the young children below the age of nine months and above. It helps them to go through that early"
}